Mycoplasma pneumoniae

Kits: EliGene® Mycoplasma Pneumoniae UNI Kit (ref: 90055-UNI)
Package size:
50 reactions
Analytical specificity: Mycoplasma pneumoniae
Specimens: sputum, bronchoalveolar lavage, nasopharyngeal swab, nasopharyngeal aspirate
Compatible instruments:
ABI 7300, ABI 7500 (FAST) (Applied Biosystems); LightCycler® 480, LightCycler® Nano, LightCycler® 2.0 (Roche); RotorGene 6000 or RotorGene Q (Qiagen); MyGo Mini, MyGo Pro (IT-IS Life Science)
CE certification: yes
Detection technology: Molecular Beacons
Clinical study description and results:
Within the frame of testing the functional characteristics of EliGene® Mycoplasma pneumoniae UNI Kit, totally 50 clinical specimens (swabs) were analyzed. The EliGene® Mycoplasma pneumoniae UNI Kit diagnosed correctly 6 specimens as Mycoplasma pneumoniae positive. Totally 44 specimens were rightly determined by EliGene® Mycoplasma pneumoniae UNI as Mycoplasma pneumoniae negative.
Sensitivity: 100 %
Specificity: 100 %
Pathogen description:
Mycoplasma pneumoniae belonging to class Mollicutes has one of the smallest known genomes. It lacks a peptidoglycan cell wall and thus it is resistant to the effects of penicillins and other beta-lactam antibiotics. In humans it causes atypical pneumonia. M. pneumoniae infects the upper and lower respiratory tracts, leading to upper respiratory tract infection, tracheobronchitis, bronchitis and community-acquired pneumonia. Infections of the lower respiratory tract generally manifest with a cough, sometimes with dyspnoea, adenopathy, wheezing and, rarely, with respiratory failure. Although M. pneumoniae infections are usually mild, and many are asymptomatic, they are not always self-limiting. M. pneumoniae causes up to 40% of cases of community-acquired pneumonia, but M. pneumoniae respiratory tract infections are also associated with a wide range of extra-pulmonary manifestations, including neurological, cardiac, dermatological, musculoskeletal, haematological and gastrointestinal symptoms.
Sánchez-Vargas FM, Gómez-Duarte OG. 2008. Mycoplasma pneumoniae-an emerging extra-pulmonary pathogen. Clin Microbiol Infect. 14(2):105-17.