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Human genetics

Coeliac disease (CE-IVD)

EliGene® Celiac DQ PLUS RT is intended for the genotypization of HLA-DQ2.5 (DQA1*05/DQB1*02), HLA-DQ2.2 (DQA1*02/DQB1*02), HLA-DQ8 (DQA1*03/DQB1*03:02) and HLA-DRB1*04 genes from isolated DNA.

EliGene® Coeliac RT is intended for the genotypization of HLA-DQ2 (DQA1*05/DQB1*02), HLA-DQ8 (DQA1*03/DQB1*03:02) and HLA-DRB1*04 genes from isolated DNA.

EliGene® Coeliac 3.0 RT is intended for the genotypization of HLA-DQ2.5 (DQA1*05/DQB1*02), HLA-DQ2.2 (DQA1*02/DQB1*02) and HLA-DQ8 (DQA1*03/DQB1*03:02) genes from isolated DNA.

This DNA diagnostic kit is based on RealTime PCR method. In this kit primers and labeled probes (FAM and JOE) for the detection of DQ2 and DQ8 alleles and for the detection of internal control are used.

Spondylitis HLA-B27 (CE-IVD)

EliGene® Spondylitis HLA-B27 RT is intended for the genotypization of HLA-B27 allele (subtypes B*2701-2759) from isolated DNA.

EliGene® Spondylitis HLA-B27 C6 is intended for the genotypization of HLA-B27 allele (subtypes B*2701-2759) from isolated DNA. The kit is designed for cobas® 6800/8800 Systems (Roche).

This DNA diagnostic kit is based on Real Time PCR method. In this kit primers and labeled probes (FAM and HEX) for the detection of HLA-B27 alleles and for the detection of internal control are used.

Lactose intolerance (CE-IVD)

EliGene® Lactose intolerance RT kit is intended for the DNA detection of C-13910T and G-22018A polymorphisms located in the regulatory region of the lactase gene from isolated DNA.

This diagnostic kit is based on RealTime PCR genotyping (allelic discrimination). In this kit primers and dual labeled probes (C-13910T FAM and HEX, G-22018A TexasRed and Cy5) for the detection of single nucleotide polymorphisms C-13910T and G-22018A in MCM6 gene from isolated DNA are used.