Chlamydophila pneumoniae

Kits: EliGene® Chlamydophila Pneumoniae UNI Kit (ref: 90057-UNI)
Package size:
50 reactions
Analytical specificity: Chlamydophila pneumoniae
Specimens: sputum, bronchoalveolar lavage, nasopharyngeal swab, nasopharyngeal aspirate
Compatible instruments:
ABI 7300, ABI 7500 (FAST) (Applied Biosystems); LightCycler® 480, LightCycler® Nano, LightCycler® 2.0 (Roche); RotorGene 6000 or RotorGene Q (Qiagen); MyGo Mini, MyGo Pro (IT-IS Life Science)
CE certification: NO (for research only)
Detection technology: Molecular Beacons
Clinical study description and results:
Within the frame of testing the functional characteristics of EliGene® Chlamydophila pneumoniae UNI Kit, totally 50 clinical specimens were analyzed. The EliGene® Chlamydophila pneumoniae UNI Kit diagnosed correctly as Chlamydophila pneumoniae positive 6 specimens. Totally 44 specimens were rightly determined by EliGene® Chlamydophila pneumoniae UNI Kit as negative.
Sensitivity: 100 %
Specificity: 100 %
Pathogen description:
Chlamydophila pneumoniae is an obligate intracellular pathogen. It is a member of the Chlamydiae, a diverse range of obligate intracellular bacteria that includes parasites of amoebae, fish, reptiles, mammals, and humans. Today C. pneumoniae is associated with a remarkably wide range of chronic diseases as meningoencephalitis, arthritis or myocarditis and it is the second most often cause of community-acquired pneumonia. C. pneumoniae spreads by drop infection but in the form of infection elementary bodies (EB) resistant to environmental stresses, it can persist on the surfaces or be spreaded by the aerosol. During the life about 80% of population is infected by C. pneumoniae however in majority of cases the infection is asymptomatic. Some forms of pneumonia can be very serious but in these cases is not clear if C. pneumoniae is not only co-pathogen.
Pignanelli S, Shurdhi A, Delucca F, et al. 2009. Simultaneous use of direct and indirect diagnostic techniques in atypical respiratory infections from Chlamydophila pneumoniae and Mycoplasma pneumoniae. J Clin Lab Anal. 23 (4): 206–9.

Roulis E, Polkinghorne A, Timms P. 2013. Chlamydia pneumoniae: modern insights into an ancient pathogen. Trends Microbiol. 21(3):120-8.